GPT-4.5 and GPT-4 both represent significant advancements in large language models, but they have different strengths and weaknesses when it comes to solving complex scientific problems.
**GPT-4 is known for its superior processing power and ability to tackle complex scientific and mathematical problems. It can solve equations in subjects like calculus, geometry, and algebra, and it has been demonstrated to analyze complex scientific concepts and simulate chemical reactions[2][6]. GPT-4's multimodal capabilities, including the integration of DALL-E for image processing, enhance its versatility in handling diverse data types[8]. Its large context window allows for more comprehensive input and output handling, which is beneficial for long-form content creation and extended conversations[6].
**GPT-4.5, on the other hand, focuses more on emotional intelligence and natural conversational abilities. While it is well-suited for tasks like writing, programming, and practical problem-solving, its performance in complex scientific and mathematical benchmarks is not as pronounced as GPT-4 or other specialized models like the o3-mini[3][7]. GPT-4.5's improvements lie in its reduced hallucination rate and enhanced pattern recognition, making it more reliable for tasks requiring factual accuracy and nuanced communication[7]. However, it may not be the optimal choice for tasks demanding advanced reasoning capabilities in science and mathematics.
In summary, while GPT-4 excels in solving complex scientific problems due to its advanced processing capabilities and multimodal features, GPT-4.5 is more geared towards tasks that require emotional intelligence and natural language understanding. For complex scientific tasks, GPT-4 or specialized reasoning models might still be preferable.
Citations:
[1] https://cdn.openai.com/gpt-4-5-system-card.pdf
[2] https://www.kommunicate.io/blog/chatgpt-4-vs-chatgpt-3-5-key-differences/
[3] https://www.businessinsider.com/openai-sam-altman-releases-gpt-4-5-emotionally-intelligent-model-2025-2
[4] https://pmc.ncbi.nlm.nih.gov/articles/PMC10884900/
[5] https://mashable.com/article/openai-gpt-4-5-release-how-to-try
[6] https://www.techtarget.com/searchenterpriseai/tip/GPT-35-vs-GPT-4-Biggest-differences-to-consider
[7] https://topmostads.com/openai-release-gpt-4-5/
[8] https://latenode.com/blog/chatgpt-4-5-and-chatgpt-5-expectations